In the subgroup of perfluoroalkyl substances (non-polymers), the compounds perfluorooctanoic acid (PFOA) and perfluorooctane sulfonic acid (PFOS) have been studied the most thoroughly. Like many PFAS, these two compounds are persistent and can now be found in the environment, the food chain and in people. PFOA and PFOS have a proven negative impact on health. Together with PFHxs and PFNA, they account for 90% of the current contamination with PFAS.
In the subgroup of polymers, a distinction is made between fluoropolymers/fluoroplastics and polymers with fluorinated side chains. The fluoropolymers consist of a carbon chain with directly attached fluorine atoms. This makes them so strong that they cannot break down into toxic substances. According to the OECD, fluoropolymers are "products of low concern", non-toxic and non-bioaccumulative, i.e. they cannot accumulate in organisms. The only danger is the possible use of toxic additives during production in the form of emulsifiers. Fluoropolymers are used, for example, in coatings, seals and cable insulation. PTFE is a fluoropolymer.
Polymers with fluorinated side chains also consist of a carbon chain, but with lateral carbon chains to which the F-atoms are first attached. As a result, these polymers are less strong, and there is a risk of losing the side chains. They are used, for example, as impregnating agents.